Frontline Plus

Treatment Guidelines:

Treat your pet once a month
with Frontline Plus at least
April through November for
protection against fleas and
ticks!

Frontline Plus

When it comes to controlling fleas and
ticks, FRONTLINE Brand Products are
the #1 recommendation of veterinarians
for flea and tick control for dogs and cats.

FRONTLINE Plus offers the long-lasting,
most complete flea and tick control
available, killing up to 100% of fleas on
your pet within 18 hours and up to 100%
of ticks on your pet within 48 hours. Best
of all, research confirms that FRONTLINE
products work for an entire month to help
keep your pet flea-free.

Visit the Frontline Plus web site:

http://frontline.us.merial.com/home/

Fleas
Few creatures can inflict more misery, ounce for ounce, than fleas.
These tiny, almost-invisible pests can make life miserable and disrupt
your household with a vicious cycle of biting and scratching. Fleas
may also cause flea allergy dermatitis in some pets and may be
carriers of dangerous diseases. All FRONTLINE products offer
control of fleas, killing up to 100% of adult fleas on your pet within 18
hours. And with an added ingredient to kill flea eggs and larvae,
FRONTLINE Plus completely breaks the life cycle of these dangerous
and annoying pests.

Ticks
Often too tiny to be seen, ticks attach to pets and feed on blood until
they are engorged. They thrive in high humidity and moderate
temperatures, but can be found all over the country. Ticks may carry
and transmit diseases, including Lyme disease, that can cause
serious health problems for pets and people. FRONTLINE Brand flea
and tick control kills up to 100% of ticks on dogs and cats within
24-48 hours.

1. How quickly do FRONTLINE Brand Products kill parasites?

Our research data shows FRONTLINE Brand Products will kill fleas within 18 hours of contact with your treated pet.
Ticks will die within 48 hours of contact with your treated pet.

2. How does FRONTLINE Plus spread over a pet's body? How long does this take?

FRONTLINE Plus spread over the pet's body by a process called translocation. When applied, these products are
gradually dispersed by the pet's natural oils, collecting in the oil glands in the skin. It is then "wicked" onto the hair over
the next 30 days. The translocation process can take up to 24 hours to complete.

3. Do fleas and ticks have to bite my pet for FRONTLINE Brand Products to work?

Fleas and ticks do not have to bite your pet for FRONTLINE Brand Products to work. FRONTLINE Brand Products kill
fleas and ticks if they simply come into contact with your pet's hair coat. The fleas will die within 18 hours of contact with
your treated pet, and ticks will die within 48 hours.

4. Why am I seeing more fleas on my pet after applying a FRONTLINE Brand Product?

After the application of a FRONTLINE Brand Product, you may see more fleas, but this is an indication that the
FRONTLINE Brand Product is working. FRONTLINE Brand Products make fleas hyper excited, drawing them to the
top of the haircoat before dying. This will make them more visible to you.

5. I treated my pet with a FRONTLINE Brand Product, but I still see fleas in my home. Why?

The fleas you see are most likely hatched flea eggs that were deposited in the environment before you began using
FRONTLINE Brand Products. Consecutive monthly applications of a FRONTLINE Brand Product to your pet will assist
with the elimination of an indoor flea life cycle. In some geographical regions in the United States, it may be required to
use the product year-round.

6. How do FRONTLINE Brand Products kill fleas before they can lay eggs on my pet?

Once new adult fleas jump on your pet, they must be present on the host for at least 24 to 36 hours before they can lay
eggs. Our research data indicates that FRONTLINE Brand Products, when used monthly, will kill your pet's fleas within
18 hours of application - before they can lay eggs.

7. Do FRONTLINE Brand Products have an expiration date?

FRONTLINE Brand Products do not carry an expiration date. We recommend storing FRONTLINE Brand Products at
room temperature and keeping them sealed in their original packaging. If stored under these conditions, FRONTLINE
Brand Products will not expire.

8. How long after application can my pet be bathed or go swimming?

FRONTLINE Brand Products remain effective for 30 days, even if a pet swims or is bathed. After application, keep the
dog or cat from getting wet until the application area appears dry, usually 24 hours. If a FRONTLINE Brand Product is
to be applied after a bath, make sure the pet is completely dry before application.

9. Can I use FRONTLINE Brand Products if my pet is on medication?

FRONTLINE Brand Products are not systemically active and have no known adverse interactions with systemic
medications.

10. Can I use FRONTLINE Brand Products if I have already applied another flea- and tick-control product?

There are no known interactions between FRONTLINE Brand Products and any other flea- and tick-control products.
However, it is recommended to wait at least 24 hours between applications.

11. Do the FRONTLINE Brand Products have any additional label claims?

Effective May 2003, FRONTLINE Plus and FRONTLINE Top Spot were approved by the Environmental Protection
Agency (EPA) to be used on pregnant, lactating and breeding dogs and cats. FRONTLINE Spray is not approved to be
used on pregnant, lactating and breeding dogs and cats. In addition, FRONTLINE Plus small size that was initially
labeled for 11-22 lb dogs has now been approved for the use on any size dog up to 22 lbs.

FRONTLINE Brand Products are now approved for the rapid elimination of chewing lice infestations on dogs and cats
and as an aid in control of sarcoptic mange infestations on dogs.

Also, any FRONTLINE Brand Product may be applied to dogs and cats as young as 8 weeks of age and older.

12. Which FRONTLINE Brand Product is right for my pet?

FRONTLINE Brand Products are available in three formulations to make it easy for you to provide your pet with the flea
and tick control that is best for them. FRONTLINE Plus is a convenient once-a-month topical product offering
long-lasting, complete control for adult fleas, flea eggs and larvae, and all four major species of ticks. FRONTLINE Top
Spot and FRONTLINE Plus provide fast-acting, long-lasting flea and tick control for dogs and cats. FRONTLINE Spray
offers quick elimination of existing flea and tick infestations. Ask your veterinarian which FRONTLINE Brand Product is
the best choice for your pet.

13. Can FRONTLINE Brand Products be used on pets other than dogs and cats?

No. FRONTLINE Brand Products are intended for use on dogs and cats only. It is not recommended for use on other
species.

14. Can FRONTLINE Brand Products be reapplied before the 30-day treatment interval is up?

Research results show that FRONTLINE Brand Products control fleas and ticks for a full month, so reapplication is
unnecessary within 30 days.

15. Where can I buy FRONTLINE Brand Products?

FRONTLINE Brand Products for dogs and cats are available from your family veterinarian.

16. Are there any side effects when using FRONTLINE?

Individual sensitivities, while rare, may occur after using any pesticide product. Since FRONTLINE Brand Products are
topical some pets may experience temporary irritation at the site of product application. If signs persist, or become
more severe within a few days of application, consult your veterinarian immediately.

17. Why are FRONTLINE Brand Products only available through my veterinarian?

It is Merial's sales policy to sell our small animal products only where a veterinarian/client/patient relationship exists.
Merial believes that the veterinarian is the only professional qualified to serve the health care needs of pets, the
concerns of their owners and the appropriate use of our small animal products such as FRONTLINE Brand Products.

18. How old does my pet have to be to apply FRONTLINE Brand Products?

All FRONTLINE Brand Products may be applied to dogs and cats as young as 8 weeks of age.

Used with permission from Merial 2007

The following FAQ is copied from
the Merial Frontline Plus Website.

Once a month protection for your pet against Fleas & Ticks

Click here for
more information
about fleas!